Chemistry–A European Journal

Enantioselective Synthesis of 2??Isoxazolines by a One??Flask Conjugate Addition/Oxime??Transfer Process

A Pohjakallio, PM Pihko

文献索引：Pohjakallio, Antti; Pihko, Petri M. Chemistry - A European Journal, 2009 , vol. 15, # 16 p. 3960 - 3964

全文：HTML全文

被引用次数: 32

摘要

Abstract Enantioselective isoxazoline synthesis: A combination of 1) a catalytic enantioselective conjugate addition of oximes to α, β-unsaturated aldehydes and 2) an acid- catalyzed intramolecular oxime-transfer reaction lead to the first asymmetric synthesis of 3- unsubstituted 2-isoxazolines (see scheme).