Polyphosphoric acid catalyzed conversion of 3-(methoxyphenyl) propionic acids to derivatives of [3.3] metacyclophane-1, 10-diones and 1-indanones

J Zhang, RL Hertzler, EM Holt, T Vickstrom…

文献索引：Zhang, Juan; Hertzler, Russell L.; Holt, Elizabeth M.; Vickstrom, Thayne; Eisenbraun, Edmund J. Journal of Organic Chemistry, 1993 , vol. 58, # 3 p. 556 - 559

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被引用次数: 5

摘要

Polyphosphoric acid (PPA) is currently the most widely used reagent for cycliacylation of 3- arylpropionic acids to the corresponding l-indan~ nes.~**~*~ We used the reaction to successfully prepare a broad series of alkyl-substituted indanonesM and more recently have prepared several known 1-indanones with mixed substitution of alkyl and methoxy groups. However, attempts to cyclize 342-methoxypheny1) propionic acid (la) and 3-(2, 4- ...