Abstract Reaction of 1, 4-benzodiazepinic N-nitrosoamidines, used as synthetic equivalents of imidoyl chlorides, with the mono-anion of tosylmethyl isocyanide is described. The process gives entry to 3-(4-tosyl) imidazo [1, 5-a][1, 4] benzodiazepines, compounds which have not been described yet in the literature. These systems can be derivatized to the corresponding trisubstituted 1, 4-benzodiazepines by alkylation or acylation of the ...
![8-chloro-6-(2-fluorophenyl)-1-methyl-3-(4-toluenesulfonyl)-4H-imidazo[1,5-a][1,4]benzodiazepine结构式](https://image.chemsrc.com/caspic/456/819793-80-1.png)
