5-Sitro-2-furonitrile has been prepared by the dehydration of 5-nitro-2-furamide with phosphorus oxychloride. Reaction of the nitrile with thioacetamide in dimethylformamide saturated with HC1 has provided 5-nitro-2-thiofuramide. The thiofuramide with a-bromo ketones has given 2-(5-nitro-2-furyl)-4-methyl-,-phenyl-, and-(5-nitro-2-furyl) thiazoles. Oxidation with iodine has provided 3, 5-bis (5-nitro-2-furyl)-l~ 2, 4-thiadiazole, 5-