Tetrahedron

A new synthesis of amino acids—II: Amidoalkylation of olefins with glyoxylic acid derivatives

D Ben-Ishai, R Moshenberg, J Altman

文献索引：Ben-Ishai,D. et al. Tetrahedron, 1977 , vol. 33, p. 1533 - 1542

全文：HTML全文

被引用次数: 33

摘要

A new synthesis of leucine, aspartie acid, aspartic acid semialdehyde and unsaturated N- acyl-α amino acid from olefins and glyoxylic acid-primary amide adducts is described. The chemistry and stereochemistry of the intermediate oxazines 7 and α-amidobutyrolactones 8 is also discussed