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Potential tetracyclic neuroleptics: 12-(4-Methylpiperazino) benzo [b] naphtho [2, 3-f] thiepin and its 12, 13-dihydro derivative

Z Kopicová, E Svátek, M Protiva

文献索引:Kopicova; Svatek; Protiva Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, # 6 p. 1960 - 1965

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被引用次数: 4

摘要

In the pres. ent synthesis we proceeded from 2.{2-naphthylthio) benzoic acid4 (VII) which was obtained by. a reaction of 2-thionaphthoI5, 6 with 2-iodobenzoic acid7 in boiling aqueous solution of potassium hydroxide in the presence of copper. The other steps were analogous to the synthesis of benzo [b] naphtho [2, 1-J] thiepin