Tetrahedron letters

An efficient and general synthesis of 3-substituted propionaldehydes using the Suzuki–Miyaura coupling

CJ Cowden, DC Hammond, BC Bishop, KMJ Brands…

文献索引：Cowden, Cameron J.; Hammond, Deborah C.; Bishop, Brian C.; Brands, Karel M.J.; Davies, Antony J.; Dolling, Ulf-H.; Brewer, Sarah E. Tetrahedron Letters, 2004 , vol. 45, # 32 p. 6125 - 6128

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被引用次数: 8

摘要

An efficient method to prepare 3-substituted propionaldehyde derivatives using a Suzuki– Miyaura coupling is reported. The reaction has been demonstrated on a range of substrates including several where the Heck reaction with allyl alcohol failed to give the desired aldehyde product.