Tetrahedron

A convenient synthesis of 4-substituted 1, 2, 3, 4-tetrahydroisoquinolin-4-ols by a novel intramolecular barbier reaction and by an insertion reaction: reaction scope …

M Kihara, M Kashimoto, Y Kobayashi

文献索引：Kihara, Masaru; Kashimoto, Minoru; Kobayashi, Yoshimaro Tetrahedron, 1992 , vol. 48, # 1 p. 67 - 78

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被引用次数: 21

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... 4-Substituted 1,2,3,4-tetrahydroisoquinolin-4-ols were prepared from -(2-iodobenzyl)phenacylamines by an intramolecular Barbier reaction with butyllithium and by an insertion reaction with zerovalent nickel. The scope and limitations of these reactions were discussed.