Tetrahedron

Efficient synthesis of 2-and 3-substituted-2, 3-dihydro [1, 4] dioxino [2, 3-b] pyridine derivatives

…, JM Leger, C Jarry, M Akssira, R Chirita, IC Grig-Alexa…

文献索引：Lazar; Soukri; Leger; Jarry; Akssira; Chirita; Grig-Alexa; Finaru; Guillaumet Tetrahedron, 2004 , vol. 60, # 31 p. 6461 - 6473

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被引用次数: 9

摘要

A versatile new approach for the synthesis in three steps of 2-substituted-2, 3-dihydro [1, 4] dioxino [2, 3-b] pyridines via a Smiles rearrangement using easily available reagents is described. A study illustrating the influence of experimental conditions on the progress of the reaction is reported.