Tetrahedron letters

On the nucleophilic tele-substitution of dichloropyrazines by metallated dithianes

…, JM Large, PN Horton, MB Hursthouse, E McDonald

文献索引：Torr, Jane E.; Large, Jonathan M.; Horton, Peter N.; Hursthouse, Michael B.; McDonald, Edward Tetrahedron Letters, 2006 , vol. 47, # 1 p. 31 - 34

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被引用次数: 11

摘要

The reaction of dichloropyrazines with a dithiane anion gave isomers of the expected formylated chloropyrazines after deprotection with methyl iodide. A tele-substitution mechanism accounts for these observations and is supported by deuterium labelling studies.