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Selective ortho and benzylic functionalization of secondary and tertiary p-tolylsulfonamides. Ipso-bromo desilylation and Suzuki cross-coupling reactions

SL MacNeil, OB Familoni…

文献索引:Hellwinkel, Dieter; Lenz, Ruediger Chemische Berichte, 1985 , vol. 118, # 1 p. 66 - 85

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被引用次数: 46

摘要

... Volume: Page ... Figure 3 2 H NMR spectra of products obtained from metalation (n-BuLi (1.1 equiv)/THF/0 °C)/CD 3 OD quench (10 equiv/0 °C ... 17 To explore the effect of additive, 1 was treated with n-BuLi/TMEDA (1:1; 2.2 equiv/THF/0 °C/15 min) followed by CD 3 ...