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Cognition-activating properties of 3-(aryloxy) pyridines

DE Butler, BPH Poschel, JG Marriott

文献索引:Butler, Donald E.; Poschel, B. P. H.; Marriott, John G. Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 346 - 350

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被引用次数: 43

摘要

4-(N-But y lN-met hylamino)-l-(m-hydroxypheny1) cyclohexan-1-one Ethylene Ketal (15b). Using the above three-step procedure and CH3 (CHz) zCOC1 as the acid chloride, there was obtained 15b (51%), mp 209-211 “C, identical in all respects (IR, NMR, and TLC) with a sample prepared by the aminonitrile method. Anal.(Cl9H&1NO3) C, H, N. Biology. Methods. The biological testing consisted of a battery of standard assays! Briefly, CF-1 female mice ...