Synthesis and biological evaluation of didemnin photoaffinity analogues

…, AJ Pfizenmayer, X Ding, D Ahuja, PL Toogood…

文献索引：Vera, Matthew D.; Pfizenmayer, Amy J.; Ding, Xiaobin; Ahuja, Deepika; Toogood, Peter L.; Joullie, Madeleine M. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 14 p. 1871 - 1874

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被引用次数: 11

摘要

The synthesis of four benzophenone-containing analogues of the antiproliferative natural product didemnin B is presented. In vitro protein biosynthesis inhibition potency and antitumor activity were evaluated. The results indicate that all four analogues are ...