Tetrahedron Letters

A very simple and highly efficient procedure for N-formylation of primary and secondary amines at room temperature under solvent-free conditions

G Brahmachari, S Laskar

文献索引：Brahmachari, Goutam; Laskar, Sujay Tetrahedron Letters, 2010 , vol. 51, # 17 p. 2319 - 2322

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被引用次数: 70

摘要

N-Formylation of primary and secondary amines has efficiently been carried out at room temperature in excellent yields by using catalytic amount of sodium formate in formic acid under solvent-free conditions. The process is remarkably simple and environmentally benign.