Chemistry Letters

An Excellent Method for Cbz-protection of Amines

K Vanlaldinpuia, HA Sema, L Rokhum, G Bez

文献索引：Vanlaldinpuia, Khiangte; Sema, H. Atoholi; Rokhum, Lalthazuala; Bez, Ghanashyam Chemistry Letters, 2010 , vol. 39, # 3 p. 228 - 229

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被引用次数: 4

摘要

Cbz-protection of aliphatic and aromatic amines can be accomplished with benzylchloroformate using a catalytic amount of dodecatungstophosphoric acid hydrate (0.05 equiv). The reaction is simple, fast, does not require aqueous work-up and gives excellent yields.