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Synthesis of heterocycles on the basis of arylation products of unsaturated compounds. 19.* Arylation of 2-acetylthio-phene and the synthesis of 2-(5-aryl-2-thien-yl)-4- …

VS Matiychuk, ND Obushak, RZ Lytvyn…

文献索引:Matiychuk; Obushak; Lytvyn; Horak, Yu. I. Chemistry of Heterocyclic Compounds, 2010 , vol. 46, # 1 p. 50 - 55

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被引用次数: 7

摘要

The reaction of 2-acetylthiophene with acetylthiophene with arenediazonium chlorides in the presence of cupric chloride as catalyst gives 2-acetyl-5-arylthiophenes. These products react with 5-chloro-and 5-bromoisatins to give 6-chloro-and 6-bromo-substituted 2-(5-aryl-2- thienyl)-4-quinolinecarboxylic acids.