Catalyst??and Base??Controlled Site??Selective sp2 and sp3 Direct Arylation of 5, 7??Dimethyl??2??phenylpyrazolo [1, 5??a] pyrimidine Using Aryl Bromides

I Bassoude, S Berteina??Raboin…

文献索引：Bassoude, Ibtissam; Berteina-Raboin, Sabine; Massip, Stephane; Leger, Jean-Michel; Jarry, Christian; Essassi, El Mokhtar; Guillaumet, Gerald European Journal of Organic Chemistry, 2012 , # 13 p. 2572 - 2578

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被引用次数: 18

摘要

Abstract The palladium-catalyzed direct C–H arylation of various heterocyclic is now recognized to be the most effective methodology for making aromatic compounds. In this paper, we present a new approach to control the site-selective direct C–H arylation of both sp 2 and sp 3 sites in 5, 7-dimethyl-2-phenylpyrazolo [1, 5-a] pyrimidine by using aryl bromides. The desired compounds were obtained in satisfactory yields. The effects of ...