Screening Multicomponent Reactions for X-Linked Inhibitor of Apoptosis-Baculoviral Inhibitor of Apoptosis Protein Repeats Domain Binder

I Monfardini, JW Huang, B Beck, JF Cellitti…

文献索引：Kolb, Juergen; Beck, Barbara; Doemling, Alexander Tetrahedron Letters, 2002 , vol. 43, # 39 p. 6897 - 6901

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被引用次数: 12

摘要

We report a second example of a general reaction screening approach to discover low molecular weight inhibitors of protein protein interactions. On the basis of the known pharmacophore model of SMAC mimetics, we predicted several inhibitors based on four