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Tetrahedron

Practical synthesis of 6-aryluridines via palladium (II) acetate catalyzed Suzuki–Miyaura cross-coupling reaction

YC Shih, TC Chien

文献索引:Shih, Yu-Chiao; Chien, Tun-Cheng Tetrahedron, 2011 , vol. 67, # 21 p. 3915 - 3923

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被引用次数: 18

摘要

Abstract Sugar-protected 6-halouridine derivatives underwent Suzuki–Miyaura cross- coupling reactions with arylboronic acids in the presence of palladium (II) acetate as a catalyst, triphenylphosphine as a ligand, and sodium carbonate as a base. This methodology is applicable to both the C5-and C6-position of uridine and provides a direct access for versatile uridine derivatives.