Tetrahedron letters

Synthesis of hemigossypol and its derivatives

J Wei, DL Vander Jagt, RE Royer, LM Deck

文献索引：Wei, Jun; Jagt, David L. Vander; Royer, Robert E.; Deck, Lorraine M. Tetrahedron Letters, 2010 , vol. 51, # 44 p. 5757 - 5760

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被引用次数: 3

摘要

Hemigossypol (3), a sesquiterpene natural product, was previously isolated from Gossypium barbadense and was shown to display improved anti-fungal activity compared to gossypol (1), the disesquiterpene dimer of hemigossypol (3). Gossypol exhibits multiple biological activities. In order to study whether hemigossypol and its derivatives retain the various bioactivities of gossypol, we developed a short and convenient synthetic scheme to ...