Tetrahedron letters

New submonomers for poly N-substituted glycines (peptoids)

T Uno, E Beausoleil, RA Goldsmith, BH Levine…

文献索引：Uno, Tetsuo; Beausoleil, Eric; Goldsmith, Richard A.; Levine, Barry H.; Zuckermann, Ronald N. Tetrahedron Letters, 1999 , vol. 40, # 8 p. 1475 - 1478

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被引用次数: 59

摘要

Five protected submonomers for peptoid synthesis were prepared, including Nin-BOC- tryptamine, Ot-butyl tyramine, PMC-guanidino-propylamine, 6-amino-6-deoxy-d- galactopyranose diacetonide, and 5-amino-2, 2-dimethyl-1, 3-dioxane. The first three mimic natural aminoacid sidechains ie tryptophan, tyrosine, and arginine, while the last two provide hydrophilic sidechains. These submonomers were successfully used for ...