Oxidative halogenation of substituted pyrroles with Cu (II). Part IV. Bromination of 2??(2′??hydroxybenzoyl) pyrrole. A new synthesis of bioactive analogs of …
S Petruso, S Bonanno, S Caronna…
文献索引：Petruso; Bonanno; Caronna; Ciofalo; Maggio; Schillaci Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 4 p. 941 - 945
Abstract The selective bromination with copper (II) bromide of the pyrrole ring in 2-(2′- hydroxybenzoyl) pyrrole II in the heterogeneous phase is described giving in almost quantitative yield the 4, 5-dibromo derivative VI. The subsequent introduction of halogen into the phenol moiety was observed when the reaction was performed in the homogeneous phase with an excess of halogenating agent. The pentabromo derivative IX, a compound ...
