Tetrahedron

Design and synthesis of bombykol analogues for probing pheromone-binding protein–ligand interactions

…, V Klusák, P Nešněrová, A Muck, J Doubský, A Svatoš

文献索引：Mansurova, Madina; Klusak, Vojtech; Nesnerova, Petra; Muck, Alexander; Doubsky, Jan; Svatos, Ales Tetrahedron, 2009 , vol. 65, # 5 p. 1069 - 1076

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被引用次数: 4

摘要

Mono-, difluorinated, and thioanalogues of Bombyx mori female sex pheromones (bombykol, 1) were designed according to the ab initio calculations. These rationally designated analogues were synthesized using hydroboration and Sonogashira coupling strategy via (5E, 7Z)-undecadien-1-ol (10) as a common intermediate. A new simplified binding assay based on nanoLC-linear ion trap ESI-MS for quantifying complexation of ...