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A synthesis of 6-(2, 5-dimethoxy-4-(2-aminopropyl) phenyl)-hexylthiol. A ligand for conjugation with fluorescent cadmium selenide/zinc sulfide core/shell …

ID Tomlinson, JL Grey, SJ Rosenthal

文献索引:Tomlinson, Ian D.; Grey, Jesse L.; Rosenthal, Sandra J. Molecules, 2002 , vol. 7, # 11 p. 777 - 790

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被引用次数: 19

摘要

Abstract: The synthesis of 6-(2, 5-dimethoxy-4-(2-aminopropyl) phenyl) hexylthiol, an agonist with a very high affinity for the 5HT 2A serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulfide core/shells via a thiol at the end of a linker arm. This conjugate has applications in biological assays and biological imaging.