The syntheses of the main toxin of Cortinarius Orellanus Fries, orellanine, and of its decomposition product, orelline, are reported. The structures of 3, 3', 4, 4'-tetrahydroxy-2, 2'- bipyridyl-N, N'-dioxide for orellanine and of 3, 3', 4, 4'-tetrahydroxy-2, 2'-bipyridyl for orelline have been proposed by WZ Antkowiak and WP Gessner. These two conpounds have now been synthesized starting from the 3, 3', 4, 4'-tetramethoxy-2, 2'-bipyridyl which could be ...
