Study of the Diastereoselectivity of Cobalt??Mediated [2+ 2+ 2] Cycloadditions of Substituted Linear Enediyne Esters

F Slowinski, C Aubert, M Malacria

文献索引：Slowinski, Franck; Aubert, Corinne; Malacria, Max European Journal of Organic Chemistry, 2001 , # 18 p. 3491 - 3500

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被引用次数: 7

摘要

Abstract The preparation of substituted linear enediyne esters bearing the double bond either at the terminal or at internal position and the ester substituent either at the alkyne or at the alkene terminus is presented. Their cobalt (I)-mediated [2+ 2+ 2] cyclizations produce the η 4-complexed tricyclic compounds in very good yields. The endo/exo selectivity depends on the position of the ester in the enediyne, but the cyclization can be totally ...