A concise synthetic approach to dihydrochalcone: First total syntheses of bipinnatone A and B

XL Zhao, HZ Li, XS Zhang, WJ Wang, SJ Da…

文献索引：Zhao, Xiao Long; Li, Hui Zhi; Zhang, Xian Shu; Wang, Wen Jing; Da, Shi Jun; Li, Ying Chinese Chemical Letters, 2011 , vol. 22, # 10 p. 1135 - 1138

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被引用次数: 1

摘要

Bipinnatone A (1) and B (2) (Fig. 1) are two novel dihydrochalcone-typed compounds, isolated from aerial parts of the Queensland shrub Boronia bipinnata by Quinn and co-workers in 2008 [1]. As shown in Ref. [1], compounds 1 and 2 can effectively inhibit the activity of hemoglobinase II which is an essential enzyme for the survival of the parasite and an attractive target for discovering the drug of malarial [2] and [3]. ... Structures of bipinnatone A and B. Structures of ...