A mild and efficient method for the synthesis of functionalized 1, 5-dien-3-ynes from 1, 3- diynes under PdII catalysis is described. The process allows quick and atom-economical assembly of various dihalo-, haloacyl-, and diacyl-substituted 1, 5-dien-3-ynes in high yields. The switch of selectivity in the formation of these dienyne products can be controlled by the choice of catalysis system and reaction conditions.
