前往化源商城

Quinoline-4-acetamides as sPLA 2 inhibitors

Y Liu, Y Feng, R Wang, Y Gao, L Lai

文献索引:Liu, Ying; Feng, Yabing; Wang, Renxiao; Gao, Ying; Lai, Luhua Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 13 p. 1639 - 1641

全文:HTML全文

被引用次数: 7

摘要

Quinoline-4-acetamides were designed as potential phospholipase A2 inhibitors by structural based method and synthesized. The chemical structures of the obtained compounds were confirmed by elemental analyses, 1H NMR and MS. Preliminary bioassay study shows that quinoline-4-acetamides display certain inhibition to sPLA2.