Tetrahedron

An improved Ullmann–Ukita–Buchwald–Li conditions for CuI-catalyzed coupling reaction of 2-pyridones with aryl halides

PS Wang, CK Liang, M Leung

文献索引：Wang, Po-Shih; Liang, Chih-Kai; Leung, Man-Kit Tetrahedron, 2005 , vol. 61, # 11 p. 2931 - 2939

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被引用次数: 37

摘要

An effective CuI-trans-N, N′-dimethylcyclohexane-1, 2-diamine (DMCDA)-K2CO3- catalyzed coupling reaction of 2-pyridones with aryl halides is described. Under our conditions, DMCDA was found to be an effective catalyst that facilitates the coupling reactions even in toluene, a common industrial solvent. In addition, 3-bromopyridine could also be coupled effectively under these conditions, indicating that the catalytic reactivity of ...