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Efficient syntheses of some versatile 3, 5-bifunctional pyrazole building blocks

…, L Penkova, G Noel, S Dechert, OA Varzatskii…

文献索引:Sachse, Anna; Penkova, Larysa; Noel, Gilles; Dechert, Sebastian; Varzatskii, Oleg A.; Fritsky, Igor O.; Meyer, Franc Synthesis, 2008 , # 5 p. 800 - 806

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被引用次数: 48

摘要

Abstract A series of convenient synthetic procedures are reported for pyrazole derivatives with carbonyl or ester groups in the 3-and 5-positions and variable substitution pattern at C4 and at the functional side arms. All compounds have been characterized by 1 H and 13 C NMR spectroscopy, elemental analyses, and mass spectrometry. In addition, the structures of several pyrazole derivatives have been determined by single crystal X-ray diffraction, ...