Birch Reductive Alkylation of Methyl m-(Hydroxymethyl) benzoate Derivatives and the Behavior of o-and p-(Hydroxymethyl) benzoates under Reductive Alkylation …

…, CM Hadad, DJ Hart, S Vyas, D Yang

文献索引：Yang, Dexi; Cwynar, Valerie; Donahue, Matthew G.; Hart, David J.; Mbogo, Grace Journal of Organic Chemistry, 2009 , vol. 74, # 22 p. 8726 - 8732

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被引用次数: 4

摘要

Birch reductive alkylation of methyl m-(hydroxymethyl) benzoate derivatives, using lithium in ammonia–tetrahydrofuran in the presence of tert-butyl alcohol, can be achieved without significant loss of benzylic oxygen substituents. Similar treatment of o-and p-(hydroxymethyl)