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Chinese Chemical Letters

Un-catalyzed tandem Knoevenagel–Michael reaction for the synthesis of 4, 4′-(arylmethylene) bis (1H-pyrazol-5-ols) in aqueous medium

NP Tale, GB Tiwari, NN Karade

文献索引:Tale, Nilesh P.; Tiwari, Girdharilal B.; Karade, Nandkishor N. Chinese Chemical Letters, 2011 , vol. 22, # 12 p. 1415 - 1418

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被引用次数: 19

摘要

A sustaining interest has been focused within the last two decades on the use of water as a medium for some well known organic reactions. Water has many advantages over general organic solvents when used as a solvent in chemical reactions. In the past, water was not used as a solvent for synthetic organic chemistry due to the low solubility and, in some cases, the instability of organic reagents in water. At the present, it has been identified that chemical reactions in ...