2, 4, 4??trisubstituted 5??amino??4h??imidazoles. A new synthetic approach and reactivity

C Avendano, T Ramos…

文献索引：Avendano, C.; Ramos, T.; Gomez-Molinero, E. Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 537 - 540

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被引用次数: 7

摘要

538 С. Avendaño, Т. Ramos and E. Gómez-Molinero Vol. 22 NH За, R = 2-pyridyl NH3 Cl~ 1bHCl,R = COOEt H* or OH" HO NH, HCl cold уУ N' 1a,R = 2-pyridyl 1byR=COOEt 4N' +N=^ Me ' Ac,0 NH3 Me-NHä I 5a, R = 2-pyridyl 5b, R = COOEt Ac-NH 6a, R = 2-pyridyl 6b,R = COOEt R'-NH 4a, R- n-Bu , Bz CONHR' 4b,R = n-Bu provided by conjugation between the C-2 substituent and the imidazole ring. An x-ray diffraction analysis of com- pounds la and 7a [12] has ...