Mechanistic and steric issues in the oxidation of phenolic and non-phenolic compounds by laccase or laccase-mediator systems. The case of bifunctional substrates
F d'Acunzo, C Galli, P Gentili, F Sergi
文献索引：D'Acunzo, Francesca; Galli, Carlo; Gentili, Patrizia; Sergi, Federica New Journal of Chemistry, 2006 , vol. 30, # 4 p. 583 - 591
Steric and redox issues of phenolic and non-phenolic substrates are investigated for a better insight of the reactivity features of the phenoloxidase laccase. Whenever a substrate is endowed with a redox potential too high for direct monoelectronic oxidation by the enzyme, or else is too much encumbered to access the enzymatic pocket, redox mediators overcome the problem, behaving as an interface between enzyme and substrate. For example, the ...
