The synthesis of pyrrolizidines. IV. Condensation of nitroparaffins with methyl methacrylate and subsequent formation of 2-, 6-and 8-alkyl-substituted pyrrolizidines

NJ Leonard, GL Shoemaker

文献索引：Leonard; Shoemaker Journal of the American Chemical Society, 1949 , vol. 71, p. 1761

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被引用次数: 8

摘要

Convenient and efficient methods of synthesis for pyrrolizidine, 8-alkylpyrrolizidines, ln2 and 1-alkylpyrrolizidinesS have been described in earlier papers. The present investigation is concerned with the condensation of nitroparaffins with methyl methacrylate and the subsequent formation of 2-alkyl-, 2, 6-dialkyl-, 2, 8-dialkyl-, and 2, 6, 8-trialkylpyrrolizidines (IV, V). The compound 2-methylpyrrolizidine (IV, R= H) had been prepared previously by ...