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Tetrahedron Letters

Direct sulfanylation of 4-hydroxycoumarins with thiols in water

YY Peng, Y Wen, X Mao, G Qiu

文献索引:Peng, Yi-Yuan; Wen, Yanfang; Mao, Xuechun; Qiu, Guanyinsheng Tetrahedron Letters, 2009 , vol. 50, # 20 p. 2405 - 2406

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被引用次数: 9

摘要

As a privileged scaffold, coumarin shows interesting biological properties. 1 The prominence of coumarin in natural products and biologically active molecules has promoted considerable efforts toward their synthesis. 2 Recently, it was found that 4-sulfanylcoumarins showed promising anti-HCV activity. 3 The discovery of promising lead antivirus compounds and their moderate activity warranted the development of efficient and rapid syntheses and evaluations of ...