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The Journal of Organic Chemistry

A new preparation of ethyl 3-oxo-4-pentenoate: a useful annelating reagent

R Zibuck, JM Streiber

文献索引:Zibuck, Regina; Streiber, Jeanne M. Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4717 - 4719

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被引用次数: 69

摘要

As part of a continuing project directed toward the total synthesis of several terpenes, we required large amounts of the well-known annelating reagent ethyl 3-oxo-4-pentenoate (1, Nazarov's reagent).'The synthesis and use of this compound as an annelating agent have been reported in the literature many time^.^-^ We required a facile, short, and efficient synthesis of 1, readily providing large quantities.