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Alkylating activity of polyphosphate ester in the course of the synthesis of benzimidazoles

GA Bistocchi, G De Meo, M Pedini, A Ricci…

文献索引:Bistocchi; De Meo; Pedini; et al. Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 9 p. 1959 - 1961

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被引用次数: 3

摘要

We have recently synthesized 1 a series of 52 benzimidazoles the majority of which showed important germicidal activity. One of these molecules, 5-fluoro-2-(5-nitro- furyl)benzimidazole (1) was remarkably active against such microbial cultures as Escherichia coli, Staphylococcus epidermidis, Salmonella typhimurium and Staphylococcus aureus2 •3 • A more detailed study of this compound's microbiological action as well as animal tests requires an efficient ...