Tetrahedron

Cerium ammonium nitrate: a new catalyst for regioselective protection of glycols

MJ Comin, E Elhalem, JB Rodriguez

文献索引：Comin, Maria J.; Elhalem, Eleonora; Rodriguez, Juan B. Tetrahedron, 2004 , vol. 60, # 51 p. 11851 - 11860

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被引用次数: 26

摘要

The regioselective introduction of a methoxymethyl (MOM) group on different type of glycols via an orthoester intermediate was investigated. The novelty presented in this study is the use of ceric ammonium nitrate instead of the previously employed camphorsulfonic acid as catalyst. The monoprotection reaction was revealed to be highly selective when the glycol moiety was in the presence of an ether functionality.