4-Aryl piperazine and piperidine amides as novel mGluR5 positive allosteric modulators

H Xiong, TA Brugel, M Balestra, DG Brown…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 24 p. 7381 - 7384

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被引用次数: 25

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Among several structurally distinct chemical assets available from a high-throughput screening (HTS) campaign to identify mGluR5 PAMS, we chose to further explore substituted acetamides of 4-aryl piperazines and piperidines 1–3 ...