A convenient method for the preparation of inverted tert-alkyl carboxylates from chiral tert-alcohols by a new type of oxidation-reduction condensation using 2, 6- …

T Mukaiyama, T Shintou…

文献索引：Mukaiyama, Teruaki; Shintou, Taichi; Fukumoto, Kentaro Journal of the American Chemical Society, 2003 , vol. 125, # 35 p. 10538 - 10539

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被引用次数: 60

摘要

It has been shown that oxidation−reduction condensation using a combination of 2,6-dimethyl-1,4-benzoquinone and alkoxydiphenylphosphines, formed in situ from alcohols and chlorodiphenylphosphine or (N,N-dimethylamino)diphenylphosphine, affords alkyl carboxylates in high yields from the corresponding alcohols and carboxylic acids by a one-pot procedure. 9 The esterification of various secondary alcohols proceeded similarly to afford the ...