The synthesis of model lactones of cyclolignan type

J Křepelka, J Holubek

文献索引：Krepelka, Jiri; Holubek, Jiri Collection of Czechoslovak Chemical Communications, 1981 , vol. 46, # 9 p. 2123 - 2128

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被引用次数: 2

摘要

Abstract Lactones VI-IX were prepared on reduction of anhydrides of 4-aryl-1- methoxynaphthalene-2, 3-dicarboxylic acids IV and V with sodium borohydride in methanol. Catalytic hydrogenation on platinum of lactones VIII and IX gave lactones with hydrogenated ring A, or A and C. Lactones XII and XIII were found to possess an inhibitory effect on the growth of the tumour S 37 in experimental animals.