Tetrahedron

A new general synthesis of sulfones from alkyl or aryl halides and p-toluenesulfonhydrazide

R Ballini, E Marcantoni, M Petrini

文献索引：Ballini, Roberto; Marcantoni, Enrico; Petrini, Marino Tetrahedron, 1989 , vol. 45, # 21 p. 6791 - 6798

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被引用次数: 27

摘要

Here we report the utilization of commercially available p-toluenesulfonhydrazide as a new nucleophilic reagent in displacement reactions with suitable halides for an improved, general synthesis of sulfones. Good results are obtained with primary, secondary, allylic, benzylic, and aromatic halides activated by withdrawing groups.