Tetrahedron

Synthese de peptides modifies incorporant un motif phosphore n ou c terminal

P Coutrot, C Grison, C Charbonnier-Gérardin

文献索引：Coutrot, Ph.; Grison, C.; Charbonnier-Gerardin, C. Tetrahedron, 1992 , vol. 48, # 45 p. 9841 - 9868

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被引用次数: 14

摘要

A general route to phosphopeptids with a 2-oxoalkylphosphonate moiety at the terminal N- aminogroup or with a 1-aminoalkylphosphonate moiety at the terminal C-carboxyl group is described. The method allows the preparation of various phosphopeptids with an α- alkylated carbon atom on the PC bond from the very available dialkylphosphonoalcanoïc acids as starting products. Phosphopeptides with a2-oxoalkylphosphonate moiety as ...