Both pyridine and benzimidazole as pharmacophoric moieties are contained in the molecules of a number of natural substances and drugs, for instance, of Cordiamin, Dibasol, Bendamustin etc.[1− 3]. As convenient synthons for preparation of potential biologically active compounds including the above heterocycles can serve 1, 1-bis (alkoxycarbonyl) ethenes containing pyridine and benzimidazole fragments. These compounds possess an ...
