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The Journal of Organic Chemistry

An Improved Procedure for the Preparation of 2-Alkyl-5-carbethoxycyclopentanone

K Sisido, K Utimoto, T Isida

文献索引:Sisido,K. et al. Journal of Organic Chemistry, 1964 , vol. 29, p. 2781 - 2782

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被引用次数: 31

摘要

1, 2, 3, 4, 5, 6, 7, 8-0ctahydro-2-quinolone(Ia).-A mixture of cyclohexanone (1960 g., 20 moles), technical acrylonitrile (1060 g., 20 moles), cyclohexylamine (101 g., 1.02 moles), and glacial acetic: acid (23 g., 0.34 moles) were heated with vigorous stirring. At go", a strongly exothermic reaction occurred; when the exotherm had subsided, heating was resumed and the mixture was maintained at 200" for 4 hr.