A strategy for generalization of the regiospecific synthesis of substituted quinones from cyclobutenediones

LS Liebeskind, KL Granberg…

文献索引：Liebeskind, Lanny S.; Granberg, Kenneth L.; Zhang, Jing Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4345 - 4352

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被引用次数: 36

摘要

Documented within is a Straightforward protocol for the synthesis of generally substituted benzoquinones and ring-fused quinones. Previously, the crucial issue of quinone substituent regiochemistry was resolved at the stage of addition of an unsaturated carbon nucleophile to a cyclobutenedione by using either symmetrically substituted cyclobutenediones or 3-alkoxy (or amino)-4-substituted-3-cyclobutenediones. In the ...