Tetrahedron

Recent progress on the iterative construction of 4-substituted-3-hydroxy benzoic acids from unsaturated aldehydes and dimethyl succinate

E Brenna, C Fuganti, V Perozzo, S Serra

文献索引：Brenna, Elisabetta; Fuganti, Claudio; Perozzo, Valentina; Serra, Stefano Tetrahedron, 1997 , vol. 53, # 44 p. 15029 - 15040

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被引用次数: 21

摘要

An improvement of a known two step cyclization procedure, affording 4-aryl-3-hydroxy benzoic acid derivatives from 3-aryl-2, 3-unsaturated aldehydes and dimethyl succinate, is described. The high versatility of the synthetic procedure is shown, as the aryl substituent can be a benzene or naphthalene moiety, or an heteroaromatic ring. It can be applied iteratively to prepare p, p'-oligophenyl derivatives.