前往化源商城

Switchable Palladium-Catalyst Reaction of Bromomethyl Sulfoxides, CO, and N-Nucleophiles: Aminocarbonylation at Csp3 versus Oxidative Carbonylation of Amines

C Mollar, C Ramirez de Arellano…

文献索引:Rodriguez, Nuria; Cuenca, Ana; Ramirez De Arellano, Carmen; Medio-Simon, Mercedes; Peine, Denissa; Asensio, Gregorio Journal of Organic Chemistry, 2004 , vol. 69, # 23 p. 8070 - 8076

全文:HTML全文

被引用次数: 10

摘要

The palladium-catalyzed reaction of α-bromomethyl sulfoxides, carbon monoxide, and N- nucleophiles follows different reaction pathways according to the catalytic system and the reaction conditions. The Pd-xantphos catalyst affords high yields of α-sulfinyl amides by an aminocarbonylation process and is the first example of this type of transformation for a nonbenzylic sp3-hybridized carbon. On the other hand, the oxidative carbonylation of ...